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Dmt and Abilify

Migrated topic.
Abilify is definitely not an SSRI. Don't know of any reason why it would be dangerous... but I'm not a doctor.
 
Abilify ie aripiprazole is a fairly novel agent with anti-pyschotic and some anti-depressant effects.It has some action on a variety of serotonin receptors, including antagonism at the 2A subtype which is where DMT has a significant agonist effect.This will result in a reduced effect of DMT.
 
Aripiprazole is a "dopamine partial agonist" ( with some partial agonism of 5HT1A receptors and blockade of subtype 2A, as corpus callosum just mentioned)
However it's an antipsychotic,despite it's novel mode of action, and I'd say that's somewhat reckless or heroic to consider using DMT during a phase where this med. was considered necessary.
But everyone in charge of their own destiny, so good luck.

peace
 
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