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DXM and Zyrtec-D (Cetirizine and Psedoephedrine)

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ethnosplendor

ethnosplendor

Rising Star
Hello,

I currently take Zyrtec-D 12 hour twice a day for my allergies. Zyrtec-D contains (Cetirizine HCI - 5 mg Antihistamine , Pseudoephedrine HCI - 120 mg Nasal Decongestant). I have read online that one should not take antihistamines and dxm together. Therefore, I have stopped taking Zyrtec-D for 24 hours. What is everyone's opinion on this? Is it safe for me to trip on DXM?

-Ethno
 
Antihistamines have some anticholinergic effects which can be hazardous with DXM, although cetirizine putatively has less anticholinergic effects than some others.

I dont think taking pseudoepehdrine regularly for allergies is wise;if you use this for more than 7-10 days on the trot, on stopping it you will get rebound nasal congestion.
 
Thank you for your reply corpus callosum. I am currently trying to end my dependency on Zyrtec-D because of the many harms of continued use. If you were in my situation would you take DXM?
 
I personally wouldnt take DXM whilst on a cetirizine/pseudoephedrine combination, nor would I advise anyone that they should.However, if I stopped the 'allergy' med and had been off off it for a few days and I felt the need for some lonnng dissociation then perhaps I might.The half life for both cetirizine and pseudoephedrine is around 8-9 hours so 5 days off it should be unproblematic.
 
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