2C-E is an amazing chemical. I've done it around 20-30 times. Each time was enjoyable.
I love the visuals. A lot more morphing and blending than other psychedelics. Straight eye candy as they say. You might become so focused on the visuals you forget about the other aspects of the trip. Nice color palette. Almost static in style. It was the only drug where I couldn't tell if my eyes were open, (This was on a 32mg dose + 125ug of LSD) By far my largest dose of any drug and something I wouldn't repeat no matter how enjoyable it was.
Physically, it's the most euphoric chemical I've put into my body, I've never done MDMA. Nonstop feelings of warmth and a great sensation all around. Smells are more potent and usually better. Tasting a bland piece of bread could become a sensational experience you won't forget. I once had spaghetti from a can, if you know what that tastes like, and thought I was eating a 5-star meal.
Mentally, it's not really "deep". Yes, it does twist your mind in similar ways to deeper psychedelics, but it's not on the same level. Ego death might occur and you might have continuously profound thoughts, but they aren't as forced. It's easier to navigate the mental aspects compared to shrooms.
I agree with dreamer042, not for an inexperienced user. I would say because the physical sensations are simply too strong. I don't think it'll be easy to freak out on, but it's so overwhelming.
For the negatives, talk about a terrible come up. I don't know if it's because I threw up on it once (don't drink lemonade and take 2C-E), but ever since I could remember, the come up is so antsy. Also the only drug I ever threw up on. What's up with that? I heard it makes a lot of people throw up.
If you're brave, my favorite combo was 12mg of 2C-E and 125 ug of LSD. The 2C-E doesn't affect LSD's headspace and it brings on an unparalleled euphoria while making the visuals deeper.
Let us know if you take it and if you do, have a great trip!