Ketamine and DMT together for fear alleviation

[smoalkiest]

Anyone suggest it, why or why not?

 

[blig-blug]

It's a different experience. Ketamine seems to really potentiate DMT while at the same time keeping one more detached from the experience (which can help with fear, as you say).

Exp. Report Thread 'Powerful experience following ketamine + DMT combination'

Jun 18, 2026

Yesterday I had an extremely powerful experience.

I was having a ketamine session, which now I have once a month. The dose was pretty heavy, and it seems I've learned to administrate it better than in the past, as it came up much faster than usual.

The session itself was powerful but with little meaning. It seemed to be focused on death, as usual for ketamine, but in a very material way. I felt myself as a clump of atoms, undifferentiated from all other atoms in the universe. I could see how the atoms that currently form me (or their components) will be here forever, mixing with...

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• dance dmt dmt experience ketamine kirtan
• Replies: 17
• Forum: DMT Experience Reports

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[brettsta]

Hi , ketamine is effective but it not good, unlike DMT that is a positive force , the spirit molecule, and should never be mixed with anything especially that , keep it pure . The only alleviation to fear is practice and training .
Seriously don't do ketamine

 

[blig-blug]

the spirit molecule, and should never be mixed with anything especially that , keep it pure

That's an opinion, which is fine, but it's not a general "should". I.e. the combination with harmalas is pretty uncontroversial to most people.

I agree mixing it with ketamine results in a different experience, and IMO it's a lesser experience. Other people prefer it.

The only alleviation to fear is practice and training

I agree.

Bear in mind the Attitude guidelines: present a statement as your opinion or else provide evidence for it.

 

[brettsta]

That's an opinion, which is fine, but it's not a general "should". I.e. the combination with harmalas is pretty uncontroversial to most people.

I agree mixing it with ketamine results in a different experience, and IMO it's a lesser experience. Other people prefer it.


I agree.

Bear in mind the Attitude guidelines: present a statement as your opinion or else provide evidence for it.

Yes I apologize it's just my opinion from experience , and I don't mean to say what you should or should not do ,
but the evidence is crystal clear ,
It had a extremely bad effect on many young people. ie bladder problems for rest of there lives .

Over 30 years I've learned to mastered the psychedelic experience , because I listened to the advice
from my inner self , and it makes it very clear , what's ok and what's not ok to do .

DMT and psilocybin are no drug , just a gift from a god .
But everyone to there own, we all look out of a different window .

 

[blig-blug]

Yes I apologize it's just my opinion from experience , and I don't mean to say what you should or should not do ,

No need to apologize, it was just a heads up. As making blanket statements can easily result in a conversation between two "X is good" and "X is bad" sides, both partly right and wrong, and both lacking nuance.

but the evidence is crystal clear ,
It had a extremely bad effect on many young people. ie bladder problems for rest of there lives .

Ketamine definitely has a very different risk profile than psychedelics. It's considerably more physically dangerous with chronic use, as you say. It also has more addictive potential. No doubt about that.

Personally, I'm in agreement with Shulgin's "just say know" in place of "just say no". When dealing with any substance, one needs to be well informed about its risk profile, the tradeoffs one is making, and be honest about one's own tendencies and particular risks. Then, one should also be honest about their use and its tradeoffs and consequences. I don't think there are inherently bad substances, but there are bad relationships with substances. And some substances are much trickier to handle in a responsible way.

So I agree that one needs to be cautious when approaching ketamine. I've found that, to me, spacing ketamine experiences out several weeks and keeping them intentional and large dose is a good balance. If I started using it casually, I think I'd end up overusing it. Anyways, I've been finding it less and less useful as time goes by.

 

[brettsta]

No need to apologize, it was just a heads up. As making blanket statements can easily result in a conversation between two "X is good" and "X is bad" sides, both partly right and wrong, and both lacking nuance.


Ketamine definitely has a very different risk profile than psychedelics. It's considerably more physically dangerous with chronic use, as you say. It also has more addictive potential. No doubt about that.

Personally, I'm in agreement with Shulgin's "just say know" in place of "just say no". When dealing with any substance, one needs to be well informed about its risk profile, the tradeoffs one is making, and be honest about one's own tendencies and particular risks. Then, one should also be honest about their use and its tradeoffs and consequences. I don't think there are inherently bad substances, but there are bad relationships with substances. And some substances are much trickier to handle in a responsible way.

So I agree that one needs to be cautious when approaching ketamine. I've found that, to me, spacing ketamine experiences out several weeks and keeping them intentional and large dose is a good balance. If I started using it casually, I think I'd end up overusing it. Anyways, I've been finding it less and less useful as time goes by.

Yes I agree with all that , totally get what you saying about statements.
K came into my life in the early 2000's at the back end of the rave scene.
I got to admit , in its place , at the end of a three day party ( rave,,) it was perfect , mind bending, and extremely
Hilarious when done collaboratory in a group , one for all and all for one .
But outside of that I could see it having a negative effect on the younger members of our group who oddly were doing it through the the week . ?

Strangely DMT is the only substance my inner self excepts , even encourages me to do, anything else including sugar , It will kick my ass .

 

[Jamie01]

Ketamine is not like DMT or like any other classical psychedelic. It does things other psychedelics don’t/can’t do outside of Iboga type alkaloids. What’s the point of comparing these things and then creating a spiritual hierarchy out of it? They are totally different things.

Sure ketamine can/probly will eliminate a lot of fear and anxiety going in but it also changes it in ways that I guess keep from repeating it. I have done it but I rarely do ketamine and have found it just combines better for me with phenethylamines like 2cb or ergolines like LSD.

I have had good trips on combinations like LSD/MDMA then a little ketamine followed by vaped DMT. Those are just wild combinations though that happened in the moment and I’m not sure I will repeat at this point in my life.

The best pre dose for DMT is psilocybin, LSD or mescaline imo.

 

[doubledog]

I have to say that I am utterly fascinated how popular ketamine is in psychedelics circles. I had it once and it felt like direct opposite of what I like in psychedelics. Disconnection instead of connection, emotionally flat instead of emotional richness etc.
I did not like it at all, second worst substance experience in my life.

 

[Jamie01]

It’s a dissociative so it would seem appropriate that it’s most efficacious when people require disassociation..it breaks the endless cycles of rumination linked to excess glutamate activity. Too much brain activity is a bad thing.