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Tetrahydroharmine (THH) and DMT taken orally

Migrated topic.
SWIM ended up taking 4 of those doses. He'll update later when his head clears. It's now 12 hours past the first dose...swim still can't sleep. Insane trip though. There was definitely nausea....but surprisingly no purge.

E.C.
 
SWIM finds that to get the most out of the THH..its best to combine 100mg THH hcl with say 40mg of harmaline...the harmaline helps a LOT with the MAO inhibition..and it also smooths out the energy from the THH...keeps you from getting over stimulated..and increases the effects dramatically..
 
The trip was very tryptamine like (the mental hell-hole he was in was like a combination of overdosing on shrooms and acid). This could have happened because swim had a total of over 200mg of dmt, ~200mg of THH, and ~200mg of harmine. The trip really didn't get going until he took the fourth dose, and that's when it started feeling like his previous oral dmt trips (with just harmaline and dmt alone), it was definitely a little different, less hectic, but still crazy scattered thoughts.

SWIM might take a good long break from this stuff, it was quite a difficult experience.

E.C.
 
Jorkest said:
SWIM finds that to get the most out of the THH..its best to combine 100mg THH hcl with say 40mg of harmaline...the harmaline helps a LOT with the MAO inhibition..and it also smooths out the energy from the THH...keeps you from getting over stimulated..and increases the effects dramatically..
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That seems about right. The subject from the previously posted tests reported, after the successful bottom threshold test of 100mg THH(hcl) + 20mg DMT(freebase), that 140 THH + 40 DMT would likely produce a good strong (but positive) experience (for that subject). Upping the harmalas to 140 using harmaline for the extra 40 instead of THH would seem like a good balance (without introducing any of the negative harmaline effects).
 
T-5:45pm 120mg harmine hcl + 80mg THH + 65mg Jungle spice Fumerate (MHRB/STB/FASA)all together with a little water and lemon juice on an empty stomach.
T-7:15pm Lift Off! Not drastic like smoking freebase but still with the uneasiness of not knowing how intense it will get.
T-7:30-9:30pm Plenty strong enough, can imagine that 200mg of DMT would be quite a difficult experience!! OEVs not too intense but strong, CEVs very intense and unbelievable colors. Felt like just being able to touch bottom of the shallow end of the pool of psychedelia but able to take excursions out into the deep end as far as wanted. Solid peak for two hours.
T-11:30pm Just about back to baseline. Nice mix, the dreamy quality of the harmine hcl was a nice place to take refuge when needed.
 
SWIM is glad that it worked out nicely for SWIY memo

he feels that THH works the best either at high doses..or with harmaline and harmine mixed with it...gives it a much harder punch
 
Did SWIY find that the psychological intensity followed the visuals? SWIM had some strong visuals before with this pharmahuasca, things turning into pastel paint blends and animated cartoony.

Then when the visuals stopped, the psychological was mentally gripping, fantastic, going totally insane for a moments. Then visuals returned and SWIM was worried it wouldn't end. In all, 5 hours. SWIM will try a stronger amount next time.

He'd like to make visuals stronger, but not have the psychological side get too much more powerful because that was at least 2X as strong as the visuals.
 
Dagger said:
Is it possible that THH by itself with DMT is stronger than when combining all three maois?
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SWIM would agree here, but on a level with the harmala junctions harmaline seems to cloud his visions alone into a more sedating level, and with THH there's a strong resemblance.. would be sensing 'the vine's deep presence, but it doesn't feel quite complete. Would definitely like to get around to harmine or even harmalol someday.
 
Possibly a daft question' but here goes anyways'


For SWIM, he needs about 200 mg of THH orally in order to feel it, or about 20 mg sublingually.

Is this because Harmala alkaloids are no absorbed very well through the gut ?

Bliss

Nobuoni +
 
Yes.

THH gets destroyed by MAO-A in the gut, that’s why it’s more potent when snorted or taken sublingually. That’s also why it’s an MAO-A inhibitor because it rapidly uses up all the MAO-A enzymes.

In fact, taking an MAOI 20 minutes before taking THH will make it work even better orally. I’ve heard that taking 100 mg of harmaline 20 minutes before taking 200 mg of THH will make the THH become “active”. I’m not sure what that means. I assume it becomes psychedelic like it does at the 350 mg dose when taken alone.

When, ayahuasca is taken by the natives, they usually take it several times over and over, so that should make the THH become “active”.

Has anyone tried taking harmaline and then THH 20 minutes later?
 
where you saying on another post Ron that the harmaline is the less sleepy more stimulating one, less foggy?
if so taking a dose of that prior to ingesting THH would be the plan of attack one would think...
 
69ron said:
Yes.

THH gets destroyed by MAO-A in the gut, that’s why it’s more potent when snorted or taken sublingually. That’s also why it’s an MAO-A inhibitor because it rapidly uses up all the MAO-A enzymes.

In fact, taking an MAOI 20 minutes before taking THH will make it work even better orally. I’ve heard that taking 100 mg of harmaline 20 minutes before taking 200 mg of THH will make the THH become “active”. I’m not sure what that means. I assume it becomes psychedelic like it does at the 350 mg dose when taken alone.

When, ayahuasca is taken by the natives, they usually take it several times over and over, so that should make the THH become “active”.

Has anyone tried taking harmaline and then THH 20 minutes later?
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On this same note,

Has anyone tried snorting THH?

Has anyone activated oral DMT with sublingual THH?
 
LLB said:
where you saying on another post Ron that the harmaline is the less sleepy more stimulating one, less foggy?
if so taking a dose of that prior to ingesting THH would be the plan of attack one would think...
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That's backwards. If I said that, it was a mistake. Harmine is the less sleepy more stimulation one, harmaline is the most sleepy foggy one. THH is neither stimulation or sedating at the normal MAOI dose used, and at those doses it doesn't affect your mind much at all. But at 350 mg and up, THH becomes psychedelic on it’s own.
 
SWIM has snorted THH and it works just about the same as sublingual..a bit faster..but it has a nasty burn...its not awful but it makes your throat raw...SWIM has also had best results with oral dmt when he takes THH with harmaline..the THH has slight stimulating effects for SWIM and the harmaline helps balance that..and if what 69ron says is correct..the harmaline blocks the mao-a and helps the THH become more active...
 
69ron said:
THH gets destroyed by MAO-A in the gut, that’s why it’s more potent when snorted or taken sublingually. That’s also why it’s an MAO-A inhibitor because it rapidly uses up all the MAO-A enzymes.
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Are you completely sure about that? I thought THH itself was a mao-a inhibitor. Harmine and harmaline is also more potent when taken sublingually. They all are VERY badly absorbed orally. I have read that the bioavailability of harmine is about 3%.
 
Jorkest said:
SWIM has snorted THH and it works just about the same as sublingual..a bit faster..but it has a nasty burn...its not awful but it makes your throat raw...SWIM has also had best results with oral dmt when he takes THH with harmaline..the THH has slight stimulating effects for SWIM and the harmaline helps balance that..and if what 69ron says is correct..the harmaline blocks the mao-a and helps the THH become more active...
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Has SWIY used sublingual THH to activate oral DMT? SWIM is considering this method purely for conservation purposes. Why take 200mg if all you need is 50mg sublingually? Does anyone have any information on what dose sublingual THH can activate oral DMT?
 
You guys don't understand how MAOIs work.

Harmine, THH, and harmine are MAO-A inhibitors. That is why they are poorly absorbed. They get bound to MAO-A in the gut instead of going into your blood stream. That's how they work. If they didn't bind to MAO-A in the gut, they wouldn't be MAO inhibitors. All MAOIs are poorly absorbed orally because they bind to MAO enzymes in the gut and get inactivated.

The reason they work is because they bind to the many MAO enzymes in your digestive system and use them all up. That then allows things like DMT to pass through the digestive system because all the harmine is bound to all the MAO-A enzymes preventing them from binding to the DMT and inactivating the DMT.

If you take an MAOI sublingually, it's going to go directly into your blood stream and bypass your digestive system. I don't think it's possible to orally activate DMT that way because all the MAO enzymes in the digestive system would still be intact and would break down the DMT.
 
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