two things important to notice is that there hasnt been a tried-and-proven tek for everybody to extract pure bufotenine (5-HO-DMT), its been general trouble to make them clean crystals, there's some nausea-making oily something that is hard to separate from it. Generally the source of bufotenine is vilca or yopo seeds
5-meo-dmt is considered by many a very weird and not very enjoyable experience. Notice the dosage of 5-meo-dmt is WAY smaller than normal DMT (nn DMT).. Which means if smoke it, start with doses more like 5mg instead of 50mg of DMT.. Also, there has been at least one case of death using 5-meo-dmt with someone that had drank ayahuasca and mixed with 5-meo-dmt.. DMT is safer. The usual source of 5-meo-dmt is either the resin of Virola trees as it is the main component, or sometimes its present in significant quantities in Chaliponga (Diplopterys cabrerana), which also contains DMT so one has to separate it.