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Endogenous DMT

Migrated topic.
I call it Jamglish, like, Jamaican English.

Fortunately not (even when my nephew, cousin and uncle are dyslexic), and I ain´t sure people I´ve clashed with would then be more forgiving. It´s just in their nature.
Peace anyway! :)
 
Master of plants said:
I call it Jamglish, like, Jamaican English.

Fortunately not (even when my nephew, cousin and uncle are dyslexic), and I ain´t sure people I´ve clashed with would then be more forgiving. It´s just in their nature.
Peace anyway! :)
Click to expand...
Thanks. I'll continue this in the Master of Plants' Hyperspace thread.
 
benzyme said:
dmt is considered by many in the scientific world to be medicinally unimportant.
Click to expand...

seems like a quite random statement. are we talking about the current medical/psychiatric reductionist paradigm? Sure maybe dmt topical use wont cure your dermatitis, but saying it is 'medically unimportant' shows that these people have a wrong attitude to begin with.

If it can provoke extreme consciousness changes, is endogenous for yet unknown reasons, and the use of dmt-containing brews showing therapeutical efficacy in some pathologies (such as depression, drug addiction and so on), then it is definitely important.


Those who make that claim seem to be fixed in the pharmaceutical 'profit' idea of what is 'medically important'.. I give a crap to what these kind of people say, no offense.

This is not to say, of course, that science should be discarded, that dmt is god inside of our selves, and that plants make dmt for us specifically, and that the red star will come in 2012 and the hyperspace alien will enlighten us all. :D
 
I simply must write this.
Humans are built up around the N, N - dimethyltryptamine. Or Logos? :)

Glad You are very happy, endlessness.
 
bufoman said:
DMT has been found to be present in all humans and does not show variations based on time or other behaviors. Thus it appears to play a role in normal waking physiology. It is not likely to play some magical role. It is not present to allow us to trip or enter HYPERSPACE. It is always present in constant amounts. There are several papers published on the subject I suggest you look into them.

DMT acts on the regions of the brain involved in sensory perception. Thus obviously it creates novel experiences, this does not mean that this is a real reality it allows us to access. This is ridiculous and completely unfounded. There are plenty of drugs which cause intense hallucinations (scopolamine) where you have communication with beings yet for some reason people have this fascination with DMT. Just because the experience is incredible and intense and meaningful doesn't mean it occurred outside of the brain in some real reality. The brian is a very powerful organ, it creates everything you know, see, taste, smell, feel, think, thus it is not difficult for it when altered to create these types of experiences.

Also dreams point out the fact that the brain is capable of generating complex sensory information without sensory input.

If people keep talking about this ridiculous alien landscape stuff people are going to think DMT makes people go crazy and i wouldn't blame them although SWIM knows plenty of people who use DMT and do not believe this crap. You are taking a hallucinogenic drug (a very potent one) and claiming the hallucinations are real. Neuroscientists know to an extent which areas of the brain these drugs act on, more research is needed but it is clear that these illusions result from an alteration of the areas of the CNS involved in perception, emotions, language and complex understanding.

Endogenous DMT may very well play a role in regulating waking sensory perception and other consciousness related processes (Wallach 2009). This would explain the complex effects and is more fascinating then believing it is present to allow us to access aliens.

Quantum Physics is more than just mere theory. Quantum Mechanic obeys very specific laws. It has been proven just because it obeys different laws than general physics does not mean it does not obey laws. It is an observation of the behavior of matter at the quantum level. It is indisputable observations. It may not be the end all logic of the universe but it is never the less an accurate observation of reality on that relative scale which is all we can ask. Anyway this means nothing however, the DMT experience is nothing like quantum mechanics. This is an absolutely ridiculous assertion. People throw around QM without understanding shit about it.
Click to expand...

Master of plants said:
Strongly disagree.

DMT is a magickal drug, which lets you look at the other side of reality (to a DMT reality), behind the curtain, to eternity full of aliens, art, dreams and magick. DMT lets you forecast future, heal, meet ancestors, or even God itself.

Reducing DMT to a mere chemical is dangerous, ideological reductionism. Remember, DMT is an sacrament!

Having an chemical structure means anything.
Click to expand...

I think both these deserve merit.

Great discussion!

Personally, I think allot can be learned by comparing the similarities/differences of the DMT world and the dream world as I believe the two are heavily intertwined. I mention this not only due to the obvious and sometimes strong change in someones dreaming behavior/experiences after they have smoked DMT on a regular basis, but because I find the two are practically the same except one way you brain has control and the other way you do (marginally speaking). I have had non-breakthrough experiences where I didn't know I was tripping or what was going on for a short period immediately after taking the hit, I would keep looking at the bong thinking I just did something (ie smoke dmt) but I couldn't remember what it was. Every time this happened I would be having fairly strong hallucinations but for some reason it wasn't obvious to me that i was tripping. It only struck me recently that maybe these short periods of confusion at the start of some trips is due to the persons consciousness been shifted so drastically that your mind tells you your dreaming but your actually awake. It is this dreaming while awake capability which I think makes DMT such an amazing substances. Dreaming has been stated by many tribal cultures and even modern theorist to be an extremely important part of a persons life and sometimes even a mystical portal to their soul, their true essence, and I believe it's this true essence which the pineal gland dictates.

Additionally, it has been proposed by Rick Strassman that the pineal gland is responsible for manufacture of endogenous dimethyltryptamine, or DMT, although this is only speculation. There are some who believe DMT has a role in dreaming and possibly near-death experiences and other mystical states and, although not proven, it was hypothesized in 1988 by Jace Callaway that DMT is connected with visual dreaming.

As I said both the comments above deserve merit as they are both true.
 
endlessness said:
benzyme said:
dmt is considered by many in the scientific world to be medicinally unimportant.
Click to expand...

seems like a quite random statement. are we talking about the current medical/psychiatric reductionist paradigm? Sure maybe dmt topical use wont cure your dermatitis, but saying it is 'medically unimportant' shows that these people have a wrong attitude to begin with.

If it can provoke extreme consciousness changes, is endogenous for yet unknown reasons, and the use of dmt-containing brews showing therapeutical efficacy in some pathologies (such as depression, drug addiction and so on), then it is definitely important.


Those who make that claim seem to be fixed in the pharmaceutical 'profit' idea of what is 'medically important'.. I give a crap to what these kind of people say, no offense.
Click to expand...

none taken; i merely restated what the modern consensus was from the Medical Hypotheses school of thought, specifically the Presti et al. 2004 paper. I'm sure dmt has therapeutic potential, particularly in sub-breakthrough doses.

This is not to say, of course, that science should be discarded, that dmt is god inside of our selves, and that plants make dmt for us specifically, and that the red star will come in 2012 and the hyperspace alien will enlighten us all. :D
Click to expand...

haha, definitely
 
Let´s make compromises.
DMT is hallucinogen with chemical structure, an magickal neurotransmitter... :)
 
stop making "reality" a democratic system.

the reality is what I create. Not the most voted system or thought
 
Master of plants said:
Let´s make compromises.
DMT is hallucinogen with chemical structure, an magickal neurotransmitter... :)
Click to expand...

It's all magickal. If you happen to have that perspective. Or not, if you don't. Obviously? If you try to question your own paradigm...

But, to recap, DMT is present in humans at all times at fairly constant levels but no one is sure why?
 
Jah said: ,,As a bonus to your CNS, you will get a dose of dmt to your head. For free." And it happened so.
 
What is the Role of D.M.T in the CNS?
-------------------------------------------------------
Hallucinogens are 5-HT2A receptors agonists.Such receptors seem to be
involved in the initiation and termination of dreams(through dopamine
activation)as deduced from introspective observations.
The main characteristic of dimethyltryptamine(D.M.T)is its
short-acting effect which,immediately,makes you think that DMT has
some specific role to play in the CNS.
Endogenous DMT,or related compounds(5-Meo-DMT),is perfectly suited in
order to be a short-acting efficient endogenous 5-HT2A agonist
produced in the initiation and termination of oneiric phenomena or/and
in other processes meant to sustain the high metabolic activity found
in oneiric phenomena.Due to the sensitivity of the 5-HT2A receptors to
downregulation by agonists the very short-acting effect of DMT at
those receptors seem then just natural in the hypothesis that DMT is
functional in oneiric phenomena.
My idea then is that DMT is used during the REM phase of dream,in
order to initiate a cascade of events which will lead to fullblown
oneiric activity.
If this is so,abnormalities of endogenous DMT pathways could lead to
spontaneous hallucinations or dream-like episodes.
The presence of an endogenous specific ligand active at 5-HT2A sites
during oneiric phenomena can also explain why these receptors
downregulate when overstimulated.It also gives an idea why 5-HT2A
antagonists are effective in schizophrenia.
In this context it would be particularly interesting to study the
eventual links between DMT and the diterpene salvinorin A as far as
REM sleep is concerned,because salvinorin A seems to trigger states
reminiscent of conscious dreaming.

 

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