Ketamine, ugh

[zknarc]

Having read about a lot of positive info about ketamine and depression I decided to try it. Anyway, I cannot say it was very positive at all and I have no idea how on earth people enjoy (or even get addicted to) it. It felt like salvia’s older evil sister had taken me on a night out and got me blackout drunk in a dark seedy dirty nightclub and ditched me.

I insufflated only 60mg which I expected would be a mild experience but instead within about 10-15mins I was totally incapacitated with a body that felt like it was made of heavy lumps of rubber. I had very strong feeling of tumbling down and being thrown around with random flashes of things that for some reason I did not recognise. I had no idea where I was, who I was or that I had taken anything but there was no fear or anxiety with it. This lasted just over 1hr.

It took almost 5hrs to be able to feel physically to walk around without any wobbliness or numbness and I was left with a heavy, dirty filthy hangover feeling that lasted the rest of the day. Not to be repeated! I can see why the regretamine label comes from. How on earth this has a reputation as a party drug I have no idea.

I have to say though, my depression does sometimes feel a reasonable amount better.

 

[Chan]

It's never been a party drug for me, and I've never understood people who describe it as such, but then, I've never been comfortable being physically incapacitated around other people...so your account doesn't tally with any of my experiences of either K or Salvia.

However, back in the day, it was an excellent post-party drug, following say, a stimulating night out with friends, laid down, and diving into a hole with some deep sounds was nirvana, or so it seemed at the time. Chuck in some 2C-B and, holy-moly...:roll:

It's a dissociative, so one shouldn't be too surprised to find oneself...dissociated. 60mg insufflated (assuming reasonable purity) is probably insufficient for a K-hole for most people, so you may have ended up "trapped between floors". For AD use, tiny bumps of 10-20mg would probably have worked better, with minimal discomfort, and possibly even some mild euphoria. Plugging might also work better for your purposes, less weird, more comfortable, paradoxically...

Nasally, it benefits greatly from first being ground up to a fine dust, in a pestle and mortar, otherwise can often be like broken glass.

Did you see recent findings about the metabolite, norketamine, probably being the principal AD agent? Perhaps you can persuade a friend to take it and collect their excreted metabolites? :shock:

 

[zknarc]

I honestly cannot imagine it being more intense. It was like hyperspacing on DMT at 5x the speed into an unfathomably deep dark place. I was totally obliterated.

Did you see recent findings about the metabolite, norketamine, probably being the principal AD agent? Perhaps you can persuade a friend to take it and collect their excreted metabolites? :shock:

Yes, that matches how I feel/felt. It took a little while afterwards for an anti-depressent feeling to come on.

 

[Ufostrahlen]

It's 10mg of K, not 60mg. 1 beer vs. 6 beers. Or 100µg vs 600µg of LSD.

Antidepressant, mood stabilizing and procognitive effects of very low dose sublingual ketamine in refractory unipolar and bipolar depression

Abstract. Intravenous ketamine (0.5 mg/kg) produces robust, rapid and long-lasting antidepressant effects, but is unpractical. Sublingual administration of

ijnp.oxfordjournals.org

 

[zknarc]

It's 10mg of K, not 60mg. 1 beer vs. 6 beers. Or 100µg vs 600µg of LSD.

Antidepressant, mood stabilizing and procognitive effects of very low dose sublingual ketamine in refractory unipolar and bipolar depression

Interesting. Those are much lower doses than mentioned elsewhere, I scaled up the typical 0.5mg/kg IV dose to what I though was a very conservative dose for insufflated based on comparable dose info available. Maybe I got some S+?

 

[Ufostrahlen]

It's 10mg of K, not 60mg. 1 beer vs. 6 beers. Or 100µg vs 600µg of LSD.

Antidepressant, mood stabilizing and procognitive effects of very low dose sublingual ketamine in refractory unipolar and bipolar depression

Interesting. Those are much lower doses than mentioned elsewhere, I scaled up the typical 0.5mg/kg IV dose to what I though was a very conservative dose for insufflated based on comparable dose info available. Maybe I got some S+?

You took too much, man.

[YOUTUBE]

Ketamine

Ketamine (also known as Ket, K, Special K, vitamin K,[5] Kitty, and others) is a classical dissociative substance of the arylcyclohexylamine class. It is perhaps the best-known and archetypal member of the dissociatives, a diverse group which includes PCP, methoxetamine, DXM, and nitrous oxide...

psychonautwiki.org

 

[Chan]

:!:

I scaled up the typical 0.5mg/kg IV dose

WTF? Where did you get that info from? 0.5mg/kg IV is far beyond typical recreational dosage and well on the way towards full anaesthesia. And there is no easy way to convert IV dosage of X to insufflated dosage of X, that I am aware of.

The correct, basic info is NOT hard to find:

Ketamine Dosage

 

[zknarc]

:!:

I scaled up the typical 0.5mg/kg IV dose

WTF? Where did you get that info from? 0.5mg/kg IV is far beyond typical recreational dosage and well on the way towards full anaesthesia. And there is no easy way to convert IV dosage of X to insufflated dosage of X, that I am aware of.

The correct, basic info is NOT hard to find:

Ketamine Dosage

This dose is mentioned in just about all literature on this:

http://www.nhs.uk/news/2014/04April/Pages/Ketamine-tested-as-severe-depression-treatment.aspx

What is Ketamine? Benefits, Risks, & Safety

Ketamine was invented in the 1960s to replace PCP. It's a powerful hallucinogenic compound that's being explored for treating depression.

howtousepsychedelics.org

Intranasal Drug Delivery in Neuropsychiatry: Focus on Intranasal Ketamine for Refractory Depression

Article Abstract Intranasal drug delivery (INDD) systems offer a route to the brain that bypasses problems related to gastrointestinal absorption, first-pass metabolism, and the blood-brain barrier; onset of therapeutic action is rapid, and the inconvenience and discomfort of parenteral...

www.psychiatrist.com

Based on your link, the dose I took should have been well inside "common" (2 steps off 'k-hole' ) I don't see the panic here.

 

[Chan]

I don't see the panic here.

There's no panic, but we have an obligation to anybody who finds this thread in the future, in search of similar relief, to present "sensible" information.

Just as you shouldn't talk to Frank, so you shouldn't ask an NHS copywriter for guidance on "street drugs". I never IV'd, but those I know who did, and were somewhat "battle-scarred," even they would rarely go above 20-30mg IV. The second link has no IV dosage info, the third link seems dead, and you had a terrible experience, following their sketchy advice. So, a bit of clarification, from an ex-user, seems warranted.

Your dose was reasonable, for someone who knew where they were going, but you wanted to go someplace else, somewhere qualitatively different, somewhere not as deep, and you'd never taken it before...

Erowid might not always be perfect, or bang-up-to-date, but it's probably the best available resource for seekers.