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Pharmahuasca

Migrated topic.
Ondansetron (Zofran) is one of the most effective anti-emetic drugs in existence. Very helpful for nausea from pharma/cactus/mushrooms.

The yellow powder is harmine hcl. The container of reddish pink orange salmon material is two something grams of spice from acacia confusa, crystals and everything turned to goo so I put it all in a silicone cannabis oil slick and it dried to this. The two wedges on the lid in middle is 100 mg of this spice.
 
Personally Zofran didn't work for me, i tried 8mgs several times on top of oral Harmalas and DMT, and it may have helped the nausea but didn't stop the purge, in fact, it was probably pretty potentiated due to the CYP inhibition of the Harmalas, it also made things feel negatively weird for me, but again, i was probably consuming a lot more than 8mgs, due to the CYP inhibition. I've also tried Peppermint, Ginger, anti-cholinergics and some other things, but nothing helped me like 10 drops of Limonene in a caspule taken with the Harmalas, completely blocks out the nausea/vomiting, ime.
 
Hi starway. Some of the capsules contain 200 mg Syrian Rue hcl extract, manske crystals. The others contain 120 mg Acacia Confusa wax, this was crystals on a bed of goo which melted into goo completely and then solidified into a salmon colored wax, it is shown in regular lighting in another post in this thread just a page back.

One 8mg ondansetron is dissolved in mouth (zofran, anti nausea), after which a harmala capsule is eaten. Take dmt capsule 20 minutes after taking harmala. Trip is four to six hours with a one hour come up.
 
hxxps://www.dmt-nexus.me/forum/default.aspx?g=posts&t=96861

2 minute formed HPBCD DMT liquid very bioavailable sublingually under tongue & outperforms DMT salts orally by many factors in personal trials, combo with tetrahydroharmine, Ayahuasca.

Part 0: 12 reasons pure THH or tetrahydroharmine rocks (this post #1 in middle)
Part 1: HPBCD complexed DMT experimental dosage, effects & duration, over 44 sublingual DMT experiences over a year's time (this post #1 at bottom with pics). Many times stronger than oral DMT. Updated 1-1-2022.

--> See the 5 hour brightly colored CEV trip report using 300mg oral THH once + 60mg sublingual HPBCD DMT + 35mg sublingual harmine fb x 2 re-doses every 1.5 hour at the very bottom of this post #1. HPBCD DMT kicks ass period. Most meaningful & intense CEV visionary experience of my life, and I've taken Ayahuasca x 70 times and high dose cactus tea over 200 times. Incredible music enhancement the whole time as well. <--

Part 2: Receptorome chart & explanation (post #2)
Part 3: 300mg Tetrahydroharmine (THH) teaching visions all by itself (post #3)
Part 4: Tetrahydroharmine receptorome similarities to mescaline; potentiates cactus & safety note (post #4)
Part 5: Chemist Patrick Arnold's HPBCD complexed prohormones for sublingual use (millions of dollars in sales) & bloodwork studies (post #5)
part 6: Dr. Narang: "with sublingual" or "under the tongue" better than buccal, gingival & palatal, absorption of drugs through the sublingual route is 3 to 10 times greater than oral route and is surpassed by hypodermic injection (post #6)
part 7: a little bit on my 70 Ayahuasca experiences, doses & visions (post #7)
part 8: New research: Morning glory contains 5 stimulating LSD-like drugs, soluble only in wine/alcohol, only sparingly soluble in water [post #8]
part 9: 20 minute visionary visit from a dead Aztec Shaman (post #9)
part 10: One way to make pure tetrahydroharmine (post #12)
part 11: From the archives of DMT world: How to easily extract 2.3g DMT from 170g bark using a 2 liter Erlenmeyer flask (post #19)
part 12: Tetrahydroharmine + 1-acetaldehyde LSD (similar to ALD-52) combo, like high dose mescaline
(page 15, post #284)
part 13: Out of print writings on the Divine Plant of the Incas, coca leaf visions...and writings on strong euphoria from coca leaf tea bags soaked in wine, forming orally active cocaethylene in the liver, discovered in 1994. Explains the popularity of Vin Mariani (coca leaf soaked wine) with both popes, Thomas Edison and countless celebrities.
[page 15, post #286]
part 14: THH + mushrooms report from JKW
(bottom of this page 1, post #20)
part 15: Multiple encounters with death and depression & 80mg DMT complexed to 560mg HPBCD oral Ayahuasca report
(bottom of this page 1, post #20)
 
I am considering trying Pharma for the first time with some harmala freebase extracted from Syrian Rue seeds by basing the tea, and with some full spectrum DMT-Fumarate (jimjam) extracted from MHRB with Xylene precipitated as fumarates using FASI. I have measured the goo + crystals that I have recovered of the Fumarates to be roughly 0.5g () so I have enough to experiment. I don't want to lowball my dosage, though I do want to tread with an abundance of caution in orchestrating my first trip.

Here is the dosage I am planning to go with:

- 200 mg Harmalas freebase consumed orally mixed in juice
- then 20 mins later take 70mg DMT-Fumarates jimjam goo with 50mg redose of harmala freebase

Would this combination and timing work for creating a moderate / medium experience with some discernible effects?

Alternatively, I could up my dose of DMT-Fumarates jimjam up to 100mg if that would be a better dose to anticipate effects.

I know starting low and working my way up is better, so how should i treat the Fumarates dosing together with freebase harmalas?

If there's a better thread out there for determining dose related concerns, please do direct me to that. Otherwise if there are any suggestions, I would appreciate the knowledge in advance.
 
brand_new_bein said:
I am considering trying Pharma for the first time

The 200 mg of freebase harmala dosage is fine. From my experience 70 mg of DMT freebase for Pharmahuasca is on the low side, when I tried that I barely got any effects. Now starting from 100 and upwards things will get REAL.
Pharma always worked for me when I took the dmt and harmalas in one single dose. It will work obviously if spaced out a little, it is a matter of convenience imo.
Redosing harmalas like you want is not needed, unless you want more dizziness and nausea.
Nailing down pharmahuasca will take a lot of trial and error from your part. I advise the boring way of starting from dosages of DMT that do not cause obvious effects like 50 mg, the slowly increase it until you find the sweet spot. This will be time consuming and taking harmalas in itself is nauseating and requires a full day from you.
So to answer your question, if you haven't had your experience, start with the method of dosing you described but eliminate the 2nd harmala redose
 
L-dreamer said:
The 200 mg of freebase harmala dosage is fine. From my experience 70 mg of DMT freebase for Pharmahuasca is on the low side, when I tried that I barely got any effects. Now starting from 100 and upwards things will get REAL.
Pharma always worked for me when I took the dmt and harmalas in one single dose. It will work obviously if spaced out a little, it is a matter of convenience imo.
Redosing harmalas like you want is not needed, unless you want more dizziness and nausea.
Nailing down pharmahuasca will take a lot of trial and error from your part. I advise the boring way of starting from dosages of DMT that do not cause obvious effects like 50 mg, the slowly increase it until you find the sweet spot. This will be time consuming and taking harmalas in itself is nauseating and requires a full day from you.
So to answer your question, if you haven't had your experience, start with the method of dosing you described but eliminate the 2nd harmala redose
Excellent advice from L-dreamer. 100mg is a really great starting point for advanced Ayahuasca drinkers. Incredibly visual & euphoric. Divine spiritual experience.

I've taken pharmahuasca close to a 100 times in a decade. Most recent 3-22-2022 experience, see post #381 on page 20:

One shot HPBCD DMT Ayahuasca, masks taste & increases absorption many factors, with 6 pics:
hxxps://www.dmt-nexus.me/forum/default.aspx?g=posts&m=1144098&#post1144098

170mg harmine fb
250mg very pure tetrahydroharmine fb
150mg HPBCD DMT dissolved (from off the spoon) into 1 shot glass of 125 degree F hot water, it dissolves instantly in the hot water, transparent color, hardly any taste at all, as the HPBCD masks the taste of the nasty DMT freebase as it goes down.

Update 4pm 3/21/2022: I am writing this 1.5 hour later: took the 1-shot HPBCD DMT Ayahuasca (150mg HPBCD DMT, 250mg THH, 170mg harmine all dissolved into 30ml hot water) and it worked incredibly well! Phenomenal strength, for the 1st 10 minutes I held on tight as it felt like I was handling a high speed sports car, ego disintegrating & boundaries shattered.

For the first 10 minutes, open or closed eyes, didn't matter, saw same thing: colored neon geometrics on the surface of everything. Felt whole body high tryptamine frequency combined with the THH frequency vibration = amazing amplified whole body frequency, like being tuned into another spirit manifested alien world. It felt like a colored shining tractor beam was going to surround me and take me away, very 3-dimensional.

It was so powerful for 10 minutes, I had to close my eyes to find a happy place. Felt like the most powerful of my past Hawaiian psychotria experiences (40 grams leaf) with Caapi which I only ventured at this dose around 5 times (and all by accident, never meant to, as it is so strong) out of my 70 total Hawaiian psychotria journeys (most 30-35 grams), this was no different, exactly the same as the potent leaf, at the very high end for advanced Ayahuasca use.

Dennis Mckenna once said about one of his Ayahuasca journeys, that for the first 10 minutes it felt like he was riding an elevator to the top floor at high speed, this is how it felt for me, or like handling a high speed sports car.

...then it became at 10 minutes extremely enjoyable, infinite open eyed beauty, incredible closed eye morphing & dancing geometrics in wild neon purple, pink & green that lasted for another 35 minutes with closed eyes. With open eyes, saturated neon colors and neon colored rainbow reflections surrounded everything which glowed intensely with an inner divine light, music playing was just heavenly, incredible music enhancement, +5 Shulgin level experience, most powerful experience I've had in years....very strong for 1.5 hour, when it decreased in strength several notches.

I could not believe the open eyed beauty--phenomenal...this is my preferred method. WOW, unbelievable experience, high euphoria, deep headspace, profound spiritual insights, extremely visual, had the power of 40g Hawaiian psychotria to the highest degree. I experienced zero nausea, zero dizziness (so long as I keep my harmine dose below 200mg). :love: :love: :love:

Full instructions for one-shot HPBCD DMT Ayahuasca:
--------------------------------------------------------------------------------
1) place 60mg of DMT onto a spoon (60mg for beginners)
2) add 1:1 molar ratio of host drug to HPBCD powder, this means 1:7 mg ratio DMT to HPBCD, use a 1:8 mg ratio DMT to HPBCD if you are using the 2-Hydroxypropyl-β-cyclodextrin.
3) this means 60mg dmt placed on spoon, then add 420mg of HPBCD on top DMT, use 480mg HPBCD if you are using the 2-Hydroxypropyl-β-cyclodextrin.
4) add 10 drops of very hot near boiling water to the mix from a nearby microwaved coffee mug for DMT doses of 90mg or below, use 12 drops of boiling hot water to mix DMT doses of 90mg or more (such as 90 to 100mg). Use 14 drops of hot water for 150mg DMT. 60mg DMT = +3 Shulgin level strength, 90mg DMT = +4 Shulgin level life strength. 150mg DMT = +5 Shulgin level life changing experience.
5) Knead or crush the HPBCD powder into the dmt using the end of another spoon for 2 minutes, scrape & mix everything back and forth hard using your muscles. This is how scientist pre-pare these complexes by kneading.
6) Optional (you do not have to do this): Hold a lighter one inch away from under the spoon to heat up spoon for 20 seconds, then pull flame away, this seems to aid dissolution or dissolving after heating up a slight bit, mix the contents 10 seconds more before using, see pics on post #381 in link above.
7) Refer to post #381 above in link with 6 pics, simply dunk spoon of HPBCD DMT into 30ml (one-shot) of 125 degree F water from microwave when ready to drink for the evening, stir a few seconds...it dissolves instantly, and leaves a transparent color it dissolves so well, then stir in around 160mg harmine fb and 150 to 300mg tetrahydroharmine freebase, add around 100mg of 100% pure vitamin C powder so the freebase harmalas can dissolve, stir a bit, then drink all at once as the Shaman's do for the most powerful journey.

Link above lists 12 reasons why you should always include pure THH or tetrahydroharmine in your Ayahuasca.

Pic 1: One shot HPBCD DMT Ayahuasca, masks taste and increases absorption many factors. Top to bottom, raw ingredients: 250mg very pure tetrahydroharmine, 170mg harmine fb, 150mg dmt fb, 1050mg HPBCD (150mg dmt x 7 = use 1050mg HPBCD to keep at a 1:1 molar ratio).

Pic 2: Chart of harmine and DMT strength from Jonathan Ott's "Ayahuasca Analogues"
 

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L-dreamer said:
This will be time consuming and taking harmalas in itself is nauseating and requires a full day from you.
Building up a harmala tolerance over several days or rather, weeks, is obviously time consuming but depending on what you have to do it won't always get in the way of other productive activities. Nor will it necessarily be nauseating. Maybe I'm lucky - with the highest harmala (rue tea) doses nowadays I get barely much beyond the faintest hint of nausea. It really has been worthwhile finding where the limits for dizziness and nausea lie with a good month of plain harmala testing. And several times, at that. Harmalas alone also present an interesting range of central effects so it bears repeating that the notion of harmalas merely being a means of orally activating DMT is worse than outdated.
 
downwardsfromzero said:
L-dreamer said:
This will be time consuming and taking harmalas in itself is nauseating and requires a full day from you.
Building up a harmala tolerance over several days or rather, weeks, is obviously time consuming but depending on what you have to do it won't always get in the way of other productive activities. Nor will it necessarily be nauseating. Maybe I'm lucky - with the highest harmala (rue tea) doses nowadays I get barely much beyond the faintest hint of nausea. It really has been worthwhile finding where the limits for dizziness and nausea lie with a good month of plain harmala testing. And several times, at that. Harmalas alone also present an interesting range of central effects so it bears repeating that the notion of harmalas merely being a means of orally activating DMT is worse than outdated.

Hopping on DF0's back, I concur. I've been working with rue daily for about a year. Now, with a 4.5g brew, I rarely get nauseated (when I do it's unusually when moving deeper in a meditative process). There's also a lot going on that's very subtle and takes mindful observation, reinforcing the idea that harmalas only for DMT activation is obsolete.

One love
 
Sublingual Ayahuasca Journey #57

Post #421 on page 22 with several pics Journal: 50 Sublingual | <span style="frontcolor:pink !Important ;">High Probability of Braindamage by Creepy non tested Drugs (forced by scammer 69ron)</span> | DMT Ayahuasca journeys over a years time - Pharmahuasca - Welcome to the DMT-Nexus Yesterday 5-20-2022, at 3pm, I used 300mg pure THH orally 45 minutes before, then 30mg harmine mixed with 120mg dmt all on a single spoon with (30 x 7 = 210mg HPBCD) + (120 x 7 = 840mg HPBCD) = 1050mg total HPBCD mixed and crushed back and forth on the spoon for 2 minutes using the end of another spoon with 10 drops boiling hot water, placed bottom side of tongue onto spoon, it all adhered as HPBCD forms sticky complexes, studies show HPBCD complexed freebase drugs increase absorption sublingually x 400 percent, held under tongue for 15 minutes, viewed incredible CEV's for 1 hour...

....this time the geometries skipped and went straight to realistic visions: I viewed incredibly beautiful women morphing into other beautiful women, all neon colored, these women changed into nearly 20 different women, completely naked and with animated face changes, infinite beauty, mind blowing CEV's...like the most incredible cartoon renderings of the most beautiful women, they even had geometric swirling pastels on the surface of their bodies...completely blown away. I usually use this at least once a week, just incredible. When I say animated, these women smiled and blew kisses and moved into all different positions...like watching a movie. They made intimate eye contact and communicated via physical motions. This was a +5 Shulgin level experience, this felt like direct communication and receiving of important artistic creative feelings and insights into the feminine domain.

I recorded this journey as one of the most visual of my entire life, never have I seen an hour's worth of beautiful women morphing into other women, with swirling geometric pastel patterns on their naked bodies, communicating physically, this is an artist's dream come true, way beyond 4k, visual detail astounding. I had headphones on, and the music sounded as if I had taken a strong bridgesii cactus tea (18" of bridgesii or around 500mg of mescaline), profound music enhancement, just heavenly, powerful spiritual insights, infinite open eyed beauty and neon colors splashed on all the walls, very powerful experience, it was so strong I started to feel the sublingual harmine/dmt starting to work in only 10 minutes, incredible blast off, lasted 1.5 hour with very strong trip, with 1 full hour of powerful closed eye visions as stated above. Zero nausea, zero dizziness, zero anxiety, fast comeup, had not used THH or DMT in two weeks, this may explain the powerful realistic visions.

The harmine and dmt needs to be taken mixed together and held under tongue at the EXACT SAME TIME, just as the Shaman's do for the most powerful experience, the harmine also helps masks the mild sting of the HPBCD DMT, it is actually comfortable under the tongue, and the sting becomes extremely mild with the harmine helping to mask.

For me, with every sublingual Ayahuasca journey, a higher level of consciousness is awake at one with being, beyond thought and the mind: the realization that all the things that truly matter - the spiritual, beauty, love, creativity, joy, inner peace - arise from beyond the mind, each journey awakens me and teaches me how to access this level of consiousness in everyday practice, to be the observer of the thinker, to rise above thought, a sense of stillness and peace, to be fully present in the moment, to feel the subtle emanation of joy arising from deep within: the joy of Being.

Pics for welcome guests (post #10): https://mycotopia.net/topic/111790-...bcd-dmt-ayahuasca-journeys-over-a-years-time/

Pic1: top to bottom: 300mg pure white tetrahydroharmine (THH) taken orally x 45 minutes before, 30mg harmine freebase, 120mg DMT freebase, 1050mg total HPBCD to complex the harmine (30mg harmine x 7 = 210mg HPBCD + 120mg dmt x 7 = 840mg HPBCD, total = 1050mg HPBCD) in 10 drops boiling hot water from a nearby coffee mug all on a single spoon.

Pic2: 30mg harmine + 120mg DMT + 1050mg HPBCD all getting ready to be mixed and mashed together on a single spoon for 2 minutes using 10 drops boiling hot water from a nearby microwaved coffee mug. Also shown at top: 300mg pure white THH in a weigher which was taken orally x 45 minutes before hand.

Pic3: This is the 30mg harmine + 120mg DMT + 1050mg HPBCD all mixed together for 2 minutes in 10 drops boiling hot water, mixed and mashed it hard back and forth using muscles, this is how scientist prepare these complexes, by kneading...then held lighter 1" away under spoon for 20 seconds, then mixed contents x 10 seconds more after light heating...this light heating guarantees the final complexing of all the ingredients, then placed tongue onto spoon, it all adhered, held for 15 minutes in sublingual mucosa, started to work strongly in only 10 minutes. Took 300mg pure tetrahydroharmine or THH orally 45 minutes before beginning the sublingual. This resulted in +5 Shulgin level life changing strength journey, extremely visual & music enhancing.
 

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I LOVE PHARMAHUASCA!
Absolutely my favorite way to trip.
The come up is incredibly euphoric for the body. I seem to be able to navigate an OEV environment, get water, pee, etc.
Yet during the peak in in a dreamy state most comfortable lying down, closing my eyes and having multiple out of body experiences.
Once I sort of come too, I like vaping a little, getting that flash sensation and really finalizing the event.

I’m 165
I first tried harmaline/dmt FB 50/50 and nothing.
Tried 100/100 and just felt the harmaline
My buddy said try 200/200 so I did.
That seems to be my magic number.
I’ve done that dosage multiple times.
One time I took a dose right before going to bed. Woke up tripping my ass off for about 1hr 😛
 
I LOVE PHARMAHUASCA!
Absolutely my favorite way to trip.
The come up is incredibly euphoric for the body. I seem to be able to navigate an OEV environment, get water, pee, etc.
Yet during the peak in in a dreamy state most comfortable lying down, closing my eyes and having multiple out of body experiences.
Once I sort of come too, I like vaping a little, getting that flash sensation and really finalizing the event.

I’m 165
I first tried harmaline/dmt FB 50/50 and nothing.
Tried 100/100 and just felt the harmaline
My buddy said try 200/200 so I did.
That seems to be my magic number.
I’ve done that dosage multiple times.
One time I took a dose right before going to bed. Woke up tripping my ass off for about 1hr 😛
Good for you (y)
By taking it together a part of the FB D will not get activated. No worries if there's plenty of D.
By taking Harmalas 1 hour in advance, same experience with half of the D weight ☺️
 
Last edited:
Good for you (y)
By taking it together a part of the FB D will not get activated. No worries if there's plenty of D.
By taking Harmalas 1 hour in advance, same experience with half of the D weight ☺️
I take the 30mins apart and that seems to really do the thing
 
Tried Pharmahuasca yesterday with no effect, would love to get pointer on where i went wrong:

Fasted for 5 hours

- 3,5gram Syrian Rue crushed to powder
- Simmered for 30 minutes in water with some lemon juice in it.
- Drank it with without straining to get eveything in my body

- Measured 70mg DMT powder
- Mixed it with lemon juice and then water
- Drank it 30 minutes after the Syrian rue

After one hour there was no real effect, so took some more DMT the same way.

Still nothing.


Where did i go wrong?
 
You may need more MAO inhibition. I'd bump your dose up between 4 and 5 grams.

Did you roast your seeds first?

One love
No roasting before, read that it wasnt really needed?

heard the Syrian Rue dosage was between 3-4 grams and the high end could cause discomfort so went with the middle ground.

You think the problem is the roasting and too low Syrian Rue dosage?

So 5 gram should be aimed for next time?
 
Did you feel the harmalas? Based on your description I would have thought that you did everything right, next to upping the dose you could eat something after dosing like a cookie or piece of bread. This can kick things into gear so to speak. Other than that I would first find your dose of the harmalas and then add the dmt. Dissolve the dmt in a couple of drops of vinegar and then add some water before chugging it down.

Good luck, it might take some trial and error but eventually you’ll be able to reliably get to the place you want to go.
 
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