Derence McTenna said:
3. No tolerance is built up (a second trip 1 hour later is just as intense), which pharmacologically means that the body is perfectly capable of dealing with DMT overdoses as any other endogenous chemical overdoses (such as glucose and insulin)
There was a time when i was happy to repeat the dose at short intervals, i don't do that now. I limit myself to one dose in any 24 hour period, this is because repeating the dose within one or two hours produced a negative response in the sense the experience was unpleasant in its visionary aspects.
Initially I thought this was a temporary effect but it seems to be more evident the older I become, and I wonder if it is age related and has something to do with the brains aging process.
I have observed this in other individuals as well, much younger than myself, the second dose very often is surprisingly dark in appearance and character compared with the first. Sometime it can be positively fearful. I've heard someone describe a similar experience with 5MeO.
It's no secret dmt has a dark side that thank fully for most people only rarely shows itself, but when it does it can come as a bit of a shock. I'm familiar enough with it now to spot the signs early on if something going critical and have developed my own techniques for dealing with it.
I have also noticed at the end of a long smoked harmine/dmt combination the tail end of the visionary sequences become rather tired and distorted, as if my brain chemistry has been depleted of its vital energy or chi, this is a very obvious sign its not a good idea to repeat the dose the same day, my brain is telling me it needs a rest.
As I said before this is more noticeable the older I become and I wonder what exactly is the mechanism and biochemistry behind it so I'm able to compensate with vitamins, supplements or whatever. So far I've not been able to figure it out. I have a hunch it may have something to do with the metabolic glucose/oxygen mechanism the brain uses to keep itself alive but this is just speculation on my part.
Strangely the effects of an oral dose produce an entirely different scenario, but I will leave that for another time.
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